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TSPAN5 Antibody, HRP conjugated

Datasheet
Code CSB-PA025163LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TSPAN5 Polyclonal antibody
Uniprot No.
P62079
Target Names
TSPAN5
Alternative Names
TSPAN5; TM4SF9; Tetraspanin-5; Tspan-5; Tetraspan NET-4; Transmembrane 4 superfamily member 9
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Tetraspanin-5 protein (114-232AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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TSPAN5 Antibodies

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Target Background

Function
Regulates ADAM10 maturation and trafficking to the cell surface. Promotes ADAM10-mediated cleavage of CD44.
Gene References into Functions
  1. intensity in villi in tubal pregnancy was significantly higher than that in normal intrauterine pregnancy PMID: 29908376
  2. Tspan5 may serve as a prognostic biomarker for predicting outcome of gastric cancer patients. Tspan5 functions as a tumour suppressor in stomach to control the tumour growth. PMID: 27223087
  3. Endothelial Tspan5- and Tspan17-ADAM10 complexes may regulate inflammation by maintaining normal VE-cadherin expression and promoting T lymphocyte transmigration. PMID: 28600292
  4. two TspanC8-specific motifs in the large extracellular domain of Tspan5 that are important for ADAM10 interaction and exit from the endoplasmic reticulum. One of the anti-Tspan5 mAbs does not recognize Tspan5 associated with ADAM10, providing a convenient way to measure the fraction of Tspan5 not associated with ADAM10. PMID: 28428248
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
Tetraspanin (TM4SF) family
Database Links

HGNC: 17753

OMIM: 613136

KEGG: hsa:10098

STRING: 9606.ENSP00000307701

UniGene: Hs.118118

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