TSSK4 Antibody

Code CSB-PA004341
Size US$100
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  • Western Blot analysis of HT29 cells using TSSK 4 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
TSSK4
Alternative Names
C14orf20 antibody; Serine/threonine-protein kinase 22E antibody; STK22E antibody; Testis-specific kinase 4 antibody; Testis-specific serine/threonine-protein kinase 4 antibody; TSK-4 antibody; TSSK-4 antibody; Tssk4 antibody; TSSK4_HUMAN antibody; TSSK5 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the Internal region of Human TSSK 4.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Serine/threonine kinase which is involved in male germ cell development and in mature sperm function. May be involved in the Cre/Creb signaling pathway. Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells. Phosphorylates CREM on 'Ser-116' in vitro. Phosphorylates ODF2 on 'Ser-95'.
Gene References into Functions
  1. TSSK4 was able to induce cell apoptosis in vitro depending on its kinase activity, which leads to abnormal testes weight and apoptosis, shedding light on its function in the process of spermatogenesis and/or spermiogenesis PMID: 25877358
  2. Observational study of gene-disease association. (HuGE Navigator) PMID: 20378615
  3. association of some single nucleotide polymorphisms in TSSK4 with male infertility. PMID: 18390560
  4. Observational study of gene-disease association. (HuGE Navigator) PMID: 18390560
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome. Cell projection, cilium, flagellum.
Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family
Tissue Specificity
Expressed only in the testis.
Database Links

HGNC: 19825

OMIM: 610711

KEGG: hsa:283629

STRING: 9606.ENSP00000339179

UniGene: Hs.314432

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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