TSTA3 Antibody

Code CSB-PA790986
Size US$297
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  • Western blot analysis of extracts from rat kidney cells and rat muscle cells, using TSTA3 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TSTA3 Polyclonal antibody
Uniprot No.
Target Names
TSTA3
Alternative Names
3 5 epimerase/4 reductase antibody; 5-epimerase-4-reductase antibody; anti TSTA3 antibody; EC 1.1.1.271 antibody; FCL_HUMAN antibody; FX antibody; GDP 4 keto 6 deoxy D mannose 3 5 epimerase 4 reductase antibody; GDP 4 keto 6 deoxy D mannose epimerase reductase antibody; GDP L fucose synthase antibody; GDP-4-keto-6-deoxy-D-mannose-3 antibody; GDP-L-fucose synthase antibody; P35B antibody; Protein FX antibody; Red cell NADP(H) binding protein antibody; Red cell NADP(H)-binding protein antibody; SDR4E1 antibody; Short chain dehydrogenase/reductase family 4E member 1 antibody; Short-chain dehydrogenase/reductase family 4E member 1 antibody; Tissue specific transplantation antigen 3 antibody; Tissue specific transplantation antigen P35B antibody; TSTA3 antibody; TSTA3 antibody antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human TSTA3.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
Gene References into Functions
  1. tissue-specific transplantation antigen P35B may serve as a novel biomarker for prognosis of patients with esophageal squamous cell carcinoma. PMID: 29950151
  2. The findings suggest that miR-125a-5p/miR-125b suppress the expression of TSTA3, which controls cell proliferation and invasion by regulating CXCR4 expression. In conclusion, a high expression of TSTA3 exerts a proto-oncogenic effect during carcinogenesis and serves as an independent molecular marker for breast cancerpatients. PMID: 26531722
  3. Data indicate that the structure of GDP-l-fucose synthase (FX) reveals the key catalytic residues. PMID: 23774504
  4. Tissue-specific transplantation antigen P35B (TSTA3) immune response-mediated metabolism coupling cell cycle to postreplication repair network in no-tumor hepatitis/cirrhotic tissues (HBV or HCV PMID: 22528125
Protein Families
NAD(P)-dependent epimerase/dehydratase family, Fucose synthase subfamily
Database Links

HGNC: 12390

OMIM: 137020

KEGG: hsa:7264

STRING: 9606.ENSP00000398803

UniGene: Hs.404119

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