TSTA3 Antibody

Code CSB-PA060020
Size US$100
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Product Details

Uniprot No.
Target Names
TSTA3
Alternative Names
3 5 epimerase/4 reductase antibody; 5-epimerase-4-reductase antibody; anti TSTA3 antibody; EC 1.1.1.271 antibody; FCL_HUMAN antibody; FX antibody; GDP 4 keto 6 deoxy D mannose 3 5 epimerase 4 reductase antibody; GDP 4 keto 6 deoxy D mannose epimerase reductase antibody; GDP L fucose synthase antibody; GDP-4-keto-6-deoxy-D-mannose-3 antibody; GDP-L-fucose synthase antibody; P35B antibody; Protein FX antibody; Red cell NADP(H) binding protein antibody; Red cell NADP(H)-binding protein antibody; SDR4E1 antibody; Short chain dehydrogenase/reductase family 4E member 1 antibody; Short-chain dehydrogenase/reductase family 4E member 1 antibody; Tissue specific transplantation antigen 3 antibody; Tissue specific transplantation antigen P35B antibody; TSTA3 antibody; TSTA3 antibody antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the C-terminal region of Human FX.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
Gene References into Functions
  1. tissue-specific transplantation antigen P35B may serve as a novel biomarker for prognosis of patients with esophageal squamous cell carcinoma. PMID: 29950151
  2. The findings suggest that miR-125a-5p/miR-125b suppress the expression of TSTA3, which controls cell proliferation and invasion by regulating CXCR4 expression. In conclusion, a high expression of TSTA3 exerts a proto-oncogenic effect during carcinogenesis and serves as an independent molecular marker for breast cancerpatients. PMID: 26531722
  3. Data indicate that the structure of GDP-l-fucose synthase (FX) reveals the key catalytic residues. PMID: 23774504
  4. Tissue-specific transplantation antigen P35B (TSTA3) immune response-mediated metabolism coupling cell cycle to postreplication repair network in no-tumor hepatitis/cirrhotic tissues (HBV or HCV PMID: 22528125
Protein Families
NAD(P)-dependent epimerase/dehydratase family, Fucose synthase subfamily
Database Links

HGNC: 12390

OMIM: 137020

KEGG: hsa:7264

STRING: 9606.ENSP00000398803

UniGene: Hs.404119

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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