TTYH1 Antibody, Biotin conjugated

Code CSB-PA867139LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TTYH1 Polyclonal antibody
Uniprot No.
Target Names
TTYH1
Alternative Names
TTYH1; Protein tweety homolog 1; hTTY1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein tweety homolog 1 protein (50-178AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable chloride channel. May be involved in cell adhesion.; Isoform 3 may be a Ca(2+)-independent and swelling-activated chloride channel, possibly involved in regulation of cell volume.
Gene References into Functions
  1. In this report, we identify tweety-homolog 1 (Ttyh1), a membrane protein linked to neuronal development, as a potent driver of tumor microtube (TM)-mediated brain colonization by glioma cells. PMID: 28607172
  2. TTYH1 was not expressed in either the malignant or the control samples PMID: 25182704
  3. Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor. PMID: 24316981
  4. Nedd4-2 differentially interacts with and regulates TTYH1-3 PMID: 18577513
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
Tweety family
Tissue Specificity
Expressed in brain, eye, ovary and testis, and at lower levels in muscle, placenta, liver and lung.
Database Links

HGNC: 13476

OMIM: 605784

KEGG: hsa:57348

UniGene: Hs.268728

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