TXNDC8 Antibody, Biotin conjugated

Code CSB-PA718200LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TXNDC8 Polyclonal antibody
Uniprot No.
Target Names
TXNDC8
Alternative Names
TXNDC8 antibody; SPTRX3 antibody; TRX6 antibody; Thioredoxin domain-containing protein 8 antibody; Spermatid-specific thioredoxin-3 antibody; Sptrx-3 antibody; Thioredoxin-6 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Thioredoxin domain-containing protein 8 protein (1-115AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm.
Gene References into Functions
  1. Data indicate that the elevated semen content of SPTRX3/TXNDC8 from assisted reproductive therapy (ART) couples coincided with reduced incidence of pregnancy by in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). PMID: 23734172
  2. SPTRX3 is a novel Golgi apparatus-associated thioredoxin, and has a role in aberrant spermatogenesis PMID: 15181017
Subcellular Location
Cytoplasm. Golgi apparatus.
Protein Families
Thioredoxin family
Tissue Specificity
Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level).
Database Links

HGNC: 31454

OMIM: 617789

KEGG: hsa:255220

STRING: 9606.ENSP00000363634

UniGene: Hs.147064

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