UBE2F Antibody

Datasheet

Code	CSB-PA850248ESR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA850248ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) UBE2F Polyclonal antibody

Uniprot No.

Q969M7

Target Names

UBE2F

Alternative Names

NCE2 antibody; NEDD8 carrier protein UBE2F antibody; NEDD8 conjugating enzyme antibody; NEDD8 conjugating enzyme UBE2F antibody; NEDD8 protein ligase UBE2F antibody; NEDD8-conjugating enzyme 2 antibody; NEDD8-conjugating enzyme UBE2F antibody; ube2f antibody; UBE2F_HUMAN antibody; Ubiquitin conjugating enzyme E2F antibody; Ubiquitin conjugating enzyme E2F (putative) antibody; Ubiquitin-conjugating enzyme E2 F antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human NEDD8-conjugating enzyme UBE2F protein (1-185AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.

Gene References into Functions

By ubiquitylating and degrading NOXA through activating CRL5, UBE2F selectively promotes lung cancer cell survival and could, therefore, serve as a novel cancer target PMID: 27591266

Protein Families

Ubiquitin-conjugating enzyme family, UBE2F subfamily

Tissue Specificity

Widely expressed (at protein level).

Database Links

HGNC: 12480

OMIM: 617700

KEGG: hsa:140739

STRING: 9606.ENSP00000272930

UniGene: Hs.471785

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Ubiquitin mediated proteolysis Target Therapy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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