UBE2F Antibody

Code CSB-PA850248ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA850248ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) UBE2F Polyclonal antibody
Uniprot No.
Target Names
UBE2F
Alternative Names
NCE2 antibody; NEDD8 carrier protein UBE2F antibody; NEDD8 conjugating enzyme antibody; NEDD8 conjugating enzyme UBE2F antibody; NEDD8 protein ligase UBE2F antibody; NEDD8-conjugating enzyme 2 antibody; NEDD8-conjugating enzyme UBE2F antibody; ube2f antibody; UBE2F_HUMAN antibody; Ubiquitin conjugating enzyme E2F antibody; Ubiquitin conjugating enzyme E2F (putative) antibody; Ubiquitin-conjugating enzyme E2 F antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human NEDD8-conjugating enzyme UBE2F protein (1-185AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
Gene References into Functions
  1. By ubiquitylating and degrading NOXA through activating CRL5, UBE2F selectively promotes lung cancer cell survival and could, therefore, serve as a novel cancer target PMID: 27591266
Protein Families
Ubiquitin-conjugating enzyme family, UBE2F subfamily
Tissue Specificity
Widely expressed (at protein level).
Database Links

HGNC: 12480

OMIM: 617700

KEGG: hsa:140739

STRING: 9606.ENSP00000272930

UniGene: Hs.471785

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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