UBE2F Antibody

Code CSB-PA025452GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
UBE2F
Alternative Names
NCE2 antibody; NEDD8 carrier protein UBE2F antibody; NEDD8 conjugating enzyme antibody; NEDD8 conjugating enzyme UBE2F antibody; NEDD8 protein ligase UBE2F antibody; NEDD8-conjugating enzyme 2 antibody; NEDD8-conjugating enzyme UBE2F antibody; ube2f antibody; UBE2F_HUMAN antibody; Ubiquitin conjugating enzyme E2F antibody; Ubiquitin conjugating enzyme E2F (putative) antibody; Ubiquitin-conjugating enzyme E2 F antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human UBE2F
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
Gene References into Functions
  1. By ubiquitylating and degrading NOXA through activating CRL5, UBE2F selectively promotes lung cancer cell survival and could, therefore, serve as a novel cancer target PMID: 27591266
Protein Families
Ubiquitin-conjugating enzyme family, UBE2F subfamily
Tissue Specificity
Widely expressed (at protein level).
Database Links

HGNC: 12480

OMIM: 617700

KEGG: hsa:140739

STRING: 9606.ENSP00000272930

UniGene: Hs.471785

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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