UGP2 Antibody

Datasheet

Code	CSB-PA620986HA01HU
Size	US$166
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Image	Western blot All lanes: UGP2 antibody at 2µg/ml + Mouse liver tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 57, 56 kDa Observed band size: 57 kDa Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA620986HA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA620986HA01HU at dilution of 1:100
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) UGP2 Polyclonal antibody

Uniprot No.

Q16851

Target Names

UGP2

Alternative Names

pHC379 antibody; UDP glucose diphosphorylase antibody; UDP glucose pyrophosphorylase 1 antibody; UDP glucose pyrophosphorylase 2 antibody; UDP glucose pyrophosphorylase antibody; UDP-glucose pyrophosphorylase antibody; UDPG antibody; UDPGP 2 antibody; UDPGP antibody; UDPGP2 antibody; UGP 1 antibody; UGP 2 antibody; UGP1 antibody; Ugp2 antibody; UGPA_HUMAN antibody; UGPase 2 antibody; UGPase antibody; UGPP 1 antibody; UGPP 2 antibody; UGPP1 antibody; UGPP2 antibody; Uridyl diphosphate glucose pyrophosphorylase 1 antibody; Uridyl diphosphate glucose pyrophosphorylase 2 antibody; UTP glucose 1 phosphate uridyltransferase antibody; UTP glucose 1 phosphate uridylyltransferase 2 antibody; UTP glucose 1 phosphate uridylyltransferase antibody; UTP--glucose-1-phosphate uridylyltransferase antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human UTP--glucose-1-phosphate uridylyltransferase protein (1-497AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The UGP2 Antibody (Product code: CSB-PA620986HA01HU) is Non-conjugated. For UGP2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA620986HB01HU	UGP2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA620986HC01HU	UGP2 Antibody, FITC conjugated
Biotin	CSB-PA620986HD01HU	UGP2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

Gene References into Functions

High UGP2 expression is associated with malignant pancreatic lesions. PMID: 29347944
This study provides clear evidence that the octameric state is a prerequisite for activity in the uridine diphosphate-glucose pyrophosphorylase. PMID: 23254995
The crystal structure was determined and shown to form octamers through end-to-end and side-by-side interactions. Mutagenesis studies showed that both dissociation of octamers and mutations of the latch loop can significantly affect the activity. PMID: 22132858
GYS1 regulation by HIF plays a central role in the hypoxic accumulation of glycogen, and hypoxia also upregulates the expression of UTP:glucose-1-phosphate urydylyltransferase (UGP2) and 1,4-alpha glucan branching enzyme (GBE1) PMID: 20300197

Subcellular Location

Cytoplasm.

Protein Families

UDPGP type 1 family

Tissue Specificity

Highly expressed in various brain regions. Expressed in amygdala, anterior cingulate cortex, caudate, cerebellar hemisphere, cerebellum, cortex, frontal cortex, hippocampus, hypothalamus, nucleus accumbens, putamen, spinal cord and substantia nigra. Also

Database Links

HGNC: 12527

OMIM: 191750

KEGG: hsa:7360

STRING: 9606.ENSP00000338703

UniGene: Hs.516217

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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