UNC13B Antibody, Biotin conjugated

Datasheet
Code CSB-PA025622LD01HU
Size US$299
Uniprot No. O14795
Immunogen Recombinant Human Protein unc-13 homolog B protein (12-215AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Protein unc-13 homolog B (Munc13-2) (munc13), UNC13B, UNC13
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Neuroscience
Target Names UNC13B
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Still Have Questions? Leave a Message or Start an on-line Chat
Function Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).
Subcellular Location Cytoplasm, Membrane, Peripheral membrane protein, Cell membrane, Cell junction, synapse
Protein Families Unc-13 family
Tissue Specificity Expressed in kidney cortical epithelial cells and brain.
Database Links

HGNC: 12566

OMIM: 605836

KEGG: hsa:10497

STRING: 9606.ENSP00000367756

UniGene: Hs.493791

Pathway Excitatory synapse pathway
Synaptic vesicle cycle

Related Products

UNC13B Antibodies

UNC13B Antibodies for Homo sapiens (Human)

UNC13B Proteins

UNC13B Proteins for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 25,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now!

We don't deal in spam.