USP48 Antibody, FITC conjugated

Datasheet
Code CSB-PA774808LC01HU
Size US$299
Uniprot No. Q86UV5
Protocols ELISA Protocol
Immunogen Recombinant Human Ubiquitin carboxyl-terminal hydrolase 48 protein (358-508AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48), USP48, USP31
Immunogen Species Homo sapiens (Human)
Research Area Cell Biology
Target Names USP48
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.
Subcellular Location Cytoplasm, Nucleus
Protein Families Peptidase C19 family
Tissue Specificity Widely expressed.
Database Links

HGNC: 18533

OMIM: 617445

KEGG: hsa:84196

STRING: 9606.ENSP00000309262

UniGene: Hs.467524

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