USP6NL Antibody

Code CSB-PA842149LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA842149LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA842149LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) USP6NL Polyclonal antibody
Uniprot No.
Target Names
USP6NL
Alternative Names
KIAA0019 antibody; Related to the N terminus of tre antibody; Related to the N-terminus of tre antibody; RN tre antibody; RN-tre antibody; RNTRE antibody; TRE2NL antibody; US6NL_HUMAN antibody; USP6 N terminal like antibody; USP6 N terminal like protein antibody; USP6 N-terminal-like protein antibody; USP6NL antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human USP6 N-terminal-like protein (387-693AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The USP6NL Antibody (Product code: CSB-PA842149LA01HU) is Non-conjugated. For USP6NL Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA842149LB01HU USP6NL Antibody, HRP conjugated ELISA
FITC CSB-PA842149LC01HU USP6NL Antibody, FITC conjugated
Biotin CSB-PA842149LD01HU USP6NL Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
Gene References into Functions
  1. Genome-wide significant (GWS) associations in single-nucleotide polymorphism (SNP)-based tests (P < 5 x 10(-8)) were identified for SNPs in PFDN1/HBEGF, USP6NL/ECHDC3, and BZRAP1-AS1. PMID: 28183528
  2. Rab5 signals to the actin cytoskeleton through RN-tre, a previously identified Rab5-specific GTPase-activating protein; RN-tre interacts with both F-actin and actinin-4, an F-actin bundling protein PMID: 15152255
Subcellular Location
Golgi apparatus. Cytoplasmic vesicle.
Tissue Specificity
Widely expressed.
Database Links

HGNC: 16858

OMIM: 605405

KEGG: hsa:9712

STRING: 9606.ENSP00000277575

UniGene: Hs.498661

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