VBP1 Antibody

Datasheet

Code	CSB-PA025808GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

P61758

Target Names

VBP1

Alternative Names

HIBBJ 46 antibody; HIBBJ46 antibody; PFD 3 antibody; PFD3 antibody; PFD3_HUMAN antibody; PFDN 3 antibody; PFDN3 antibody; Prefoldin 3 antibody; Prefoldin subunit 3 antibody; Prefoldin3 antibody; VBP 1 antibody; VBP-1 antibody; VBP1 antibody; VHL binding protein 1 antibody; VHL-binding protein 1 antibody; Von Hippel Lindau binding protein 1 antibody; Von Hippel-Lindau-binding protein 1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human VBP1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC,IF

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Gene References into Functions

Data show that von Hippel-Lindau-binding protein 1 (VBP1) enhances the stability of von Hippel-Lindau tumor suppressor protein (pVHL) and facilitates pVHL-mediated ubiquitination of hypoxia-inducible factor 1, alpha subunit (HIF-1alpha). PMID: 29121446
VBP1 acts together with p97 to regulate hMSH4 degradation. PMID: 23964080
binds to HIF-1 alpha and regulates the function of HIF-1 alpha PMID: 12613020
VBP1 and cullin2/von Hippel-Lindau are required for proper HIV-1 expression at a step between integrase-dependent proviral integration into the host genome and transcription of viral genes PMID: 17698809

Subcellular Location

Cytoplasm. Nucleus. Note=In complex with VHL can translocate to the nucleus.

Protein Families

Prefoldin subunit alpha family

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 12662

OMIM: 300133

KEGG: hsa:7411

STRING: 9606.ENSP00000286428

UniGene: Hs.436803

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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