VDAC1 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA865954LD01DOA
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana VDAC1 Polyclonal antibody

Uniprot No.

Q9SRH5

Target Names

VDAC1

Alternative Names

VDAC1 antibody; At3g01280 antibody; T22N4.9 antibody; Mitochondrial outer membrane protein porin 1 antibody; Voltage-dependent anion-selective channel protein 1 antibody; AtVDAC1 antibody; VDAC-1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana Mitochondrial outer membrane protein porin 1 protein (2-276AA)

Immunogen Species

Arabidopsis thaliana

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Involved in plant development at reproductive stage, is important for pollen development and may regulate hydrogen peroxide generation during disease resistance.

Gene References into Functions

Abnormal ovules in the process of female gametogenesis were observed. Both mitochondrial transmembrane potential and ATP synthesis rate were obviously reduced in the mitochondria isolated from atvdac1 plants. PMID: 25192453
Data indicate that both voltage-dependent anion channel 1 (AtVDAC1) and calcium sensor CBL1 regulate cold stress responses during seed germination and plant development. PMID: 23344040
AtVDAC1 has a main function in mitochondria PMID: 22294207
VDAC1 is not only necessary for normal growth but also important for disease resistance through regulation of hydrogen peroxide generation. PMID: 21705391

Subcellular Location

Mitochondrion outer membrane.

Protein Families

Eukaryotic mitochondrial porin (TC 1.B.8.1) family

Tissue Specificity

Expressed in shoot meristems, root meristematic zone, lateral roots, leaves, stigma and anthers.

Database Links

KEGG: ath:AT3G01280

STRING: 3702.AT3G01280.1

UniGene: At.24885

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Related pathways

Calcium signaling pathway Cellular senescence Necroptosis NOD-like receptor signaling pathway cGMP-PKG signaling pathway Cholesterol metabolism

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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