VPREB3 Antibody

Code CSB-PA891724LA01HU
Size US$299 How to order?
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) VPREB3 Polyclonal antibody
Uniprot No. Q9UKI3
Target Names VPREB3
Alternative Names N27C7 2 antibody; N27C7-2 antibody; Pre B lymphocyte protein 3 antibody; Pre-B lymphocyte protein 3 antibody; PRO619 antibody; Protein VPreB3 antibody; UNQ355 antibody; VPRE3_HUMAN antibody; VPREB3 antibody; VpreB3 protein antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Pre-B lymphocyte protein 3 protein (21-122AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated

The VPREB3 Antibody (Product code: CSB-PA891724LA01HU) is Non-conjugated. For VPREB3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA891724LB01HU VPREB3 Antibody, HRP conjugated ELISA
FITC CSB-PA891724LC01HU VPREB3 Antibody, FITC conjugated
Biotin CSB-PA891724LD01HU VPREB3 Antibody, Biotin conjugated ELISA
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells.
Gene References into Functions
  1. A possible role for VPREB3 in aldosterone biosynthesis. PMID: 25861052
  2. levels of VPREB3 mRNA in aldosterone-producing adenomas directly correlate to plasma aldosterone concentrations in peripheral blood of respective patients PMID: 25861052
  3. mouse VpreB3 associates with mu heavy chains early in pre-B cell receptor biosynthesis PMID: 8491176
  4. VpreB3 may play a role in the regulation of the maturation and secretion of free IgLC in chicken B cells PMID: 14670953
  5. the combined immunohistochemical detection of VPREB3 and ID3 is applicable to the routine diagnostic in case of mature aggressive B-cell lymphomas. PMID: 24493312
  6. Data show that the absence of VpreB3 is virtually always associated with wild-type c-MYC alleles. PMID: 20823132
  7. the present study confirms the co-existence of surrogate lambda and kappa receptors that are proposed to work in concert to promote B lymphocyte maturation. PMID: 15757909

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Protein Families Immunoglobulin superfamily
Tissue Specificity Expressed in B-cell precursors. Expressed in fetal liver, bone marrow, spleen and lymph node.
Database Links

HGNC: 12710

OMIM: 605017

KEGG: hsa:29802

STRING: 9606.ENSP00000248948

UniGene: Hs.136713

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