VPS26A Antibody

Datasheet
Code CSB-PA025898LB11HU
Size US$299

Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) VPS26A Polyclonal antibody
Uniprot No. O75436
Target Names VPS26A
Alternative Names Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26), VPS26A, VPS26
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Vacuolar protein sorting-associated protein 26A protein (21-180AA)
Immunogen Species Homo sapiens (Human)
Conjugate HRP
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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Target Data

Function Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins (Probable). The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5 (Probable). Required for retrograde transport of lysosomal enzyme receptor IGF2R
Subcellular Location Cytoplasm, Endosome membrane, Peripheral membrane protein, Early endosome
Protein Families VPS26 family
Database Links

HGNC: 12711

OMIM: 605506

KEGG: hsa:9559

STRING: 9606.ENSP00000263559

UniGene: Hs.499925

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