VPS28 Antibody

Code CSB-PA892327LA01HU
Size US$166
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Image
  • IHC image of CSB-PA892327LA01HU diluted at 1:200 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) VPS28 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28), VPS28
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Vacuolar protein sorting-associated protein 28 homolog protein (1-221aa)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The VPS28 Antibody (Product code: CSB-PA892327LA01HU) is Non-conjugated. For VPS28 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA892327LB01HU VPS28 Antibody, HRP conjugated ELISA
FITC CSB-PA892327LC01HU VPS28 Antibody, FITC conjugated
Biotin CSB-PA892327LD01HU VPS28 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:100-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.
Gene References into Functions
  1. CIIA attenuates neurotoxicity caused by OGD/R through inhibiting ASK1-dependent signaling events. PMID: 25098452
  2. USP8, and the endosomal sorting protein, VPS28, are the negative regulators of NOD2-induced IL-8 secretion. PMID: 25170077
  3. CIIA functions as a negative modulator of the SOS1-Ras signaling events initiated by peptide growth factors including EGF. PMID: 24522193
  4. EIAV Gag interacts with a cellular component of the VPS machinery, VPS28, to accomplish efficient particle release PMID: 12857913
Subcellular Location
Cell membrane. Late endosome membrane; Peripheral membrane protein.
Protein Families
VPS28 family
Database Links

HGNC: 18178

OMIM: 611952

KEGG: hsa:51160

STRING: 9606.ENSP00000366565

UniGene: Hs.418175

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