WNT7A Antibody, Biotin conjugated

Datasheet
Code CSB-PA026141LD01HU
Size US$299
Uniprot No. O00755
Protocols ELISA Protocol
Immunogen Recombinant Human Protein Wnt-7a protein (126-302AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity).
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Protein Wnt-7a, WNT7A
Immunogen Species Homo sapiens (Human)
Research Area Stem Cells
Target Names WNT7A
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity).
Involvement in disease Limb pelvis hypoplasia aplasia syndrome (LPHAS); Fuhrmann syndrome (FUHRS)
Subcellular Location Secreted, extracellular space, extracellular matrix
Protein Families Wnt family
Tissue Specificity Expression is restricted to placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain.
Database Links

HGNC: 12786

OMIM: 228930

KEGG: hsa:7476

STRING: 9606.ENSP00000285018

UniGene: Hs.72290

Pathway Hippo signaling pathway
Melanogenesis
mTOR signaling pathway
Wnt signaling pathway
Signaling pathways regulating pluripotency of stem cells

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