WNT9B Antibody, HRP conjugated

1. Our study further supports the involvement of WNT9B as a cleft susceptibility gene in Brazilian families experiencing NSCL+/-P. Although additional studies are still necessary to unveil the exact mechanism by which WNT genes would contribute to NSCL+/-P, allelic polymorphisms in these genes and their interactions may partly explain the variance of individual susceptibility to NSCL+/-P. PMID: 24437584
2. Multi-layered mutation in hedgehog-related genes in Gorlin syndrome may affect the phenotype PMID: 28915250
3. This association study successfully identified two susceptibility Single Nucleotide Polymorphisms, (WNT9B and PBX1) associated with Mayer-Rokitansky-Kuster-Hauser syndrome risk, both separately and interactively. PMID: 26075712
4. results indicate that mutations in the coding sequence of WNT9B are not responsible for Mullerian duct abnormalities in the Chinese population PMID: 24581601
5. Two novel mutations (a missense mutation in exon 1, and one in the 3-UTR) may be pathogenic variants in Mayer-Rokitansky-Kuster-Hauser syndrome patients and warrant further functional study. PMID: 24268733
6. The signals from the stromal fibroblasts cooperate with Wnt9b to promote differentiation of the progenitor cells. PMID: 23974041

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HGNC: 12779

OMIM: 602864

KEGG: hsa:7484

STRING: 9606.ENSP00000290015

UniGene: Hs.326420