XK Antibody

Code CSB-PA908755
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA908755(XK Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA908755(XK Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human normal liver and placenta tissue, Primary antibody: CSB-PA908755(XK Antibody) at dilution 1/350 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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Product Details

Uniprot No.
Target Names
XK
Alternative Names
XK antibody; XKR1 antibody; XRG1 antibody; Membrane transport protein XK antibody; Kell complex 37 kDa component antibody; Kx antigen antibody; XK-related protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human XK
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
IHC 1:20-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.
Gene References into Functions
  1. the expression of KX is critical to normal morphology, and null mutations are associated with the McLeod neuroacanthocytosis syndrome. PMID: 26308465
  2. The XK gene was not linked to hypermutability in red cells from patients with paroxysmal nocturnal hemoglobinuria. PMID: 24816235
  3. study reports the clinical findings and a novel nonsense hemizygous mutation, c.154C>T (p.Gln52X) at exon 1 of XK gene in a Taiwanese family with McLeod syndrome PMID: 24635891
  4. Novel XK protein mutations are reported in two patients who exhibit typical clinical characteristics of McLeod syndrome. PMID: 21463873
  5. This study identified one non-synonymous and one intron variant in mood disorder and schizophrenia subjects, respectively, in XK. PMID: 21145924
  6. In human cortex, the results show expression of XK in cortical neurons with an apparent cytoplasmic localization. PMID: 17379193
  7. Sequence analysis demonstrated a 5 bp deletion in exon 2 of the XK gene in McLeod syndrome. PMID: 17469188

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Involvement in disease
McLeod syndrome (MLS)
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
XK family
Tissue Specificity
High levels in skeletal muscle, heart, brain, and pancreas; low levels in placenta, lung, liver, and kidney.
Database Links

HGNC: 12811

OMIM: 300842

KEGG: hsa:7504

STRING: 9606.ENSP00000367879

UniGene: Hs.78919

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