XPR1 Antibody

Code CSB-PA871381LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA871381LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA871381LA01HU at dilution of 1:100

  • Immunofluorescent analysis of Hela cells using CSB-PA871381LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) XPR1 Polyclonal antibody
Uniprot No.
Target Names
XPR1
Alternative Names
FLJ90308 antibody; OTTHUMP00000033084 antibody; OTTHUMP00000033085 antibody; Polytropic murine leukamia virus receptor SYG 1 antibody; Polytropic murine leukamia virus receptor SYG1 antibody; Protein SYG1 homolog antibody; SYG 1 antibody; SYG1 antibody; SYG1 protein antibody; X-receptor antibody; X3 antibody; Xenotropic and polytropic murine leukemia virus receptor X3 antibody; Xenotropic and polytropic retrovirus receptor antibody; Xenotropic and polytropic retrovirus receptor 1 antibody; XPR 1 antibody; XPR1 antibody; XPR1 protein antibody; XPR1_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Xenotropic and polytropic retrovirus receptor 1 protein (529-696AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The XPR1 Antibody (Product code: CSB-PA871381LA01HU) is Non-conjugated. For XPR1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA871381LB01HU XPR1 Antibody, HRP conjugated ELISA
FITC CSB-PA871381LC01HU XPR1 Antibody, FITC conjugated
Biotin CSB-PA871381LD01HU XPR1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules.
Gene References into Functions
  1. These results confirm that loss of XPR1-mediated phosphate export function causes primary familial brain calcification, occurring in less than 8 % of cases negative for the other genes, and may be responsible for parkinsonism. PMID: 27230854
  2. XPR1 mutations alter phosphate export and phosphate homeostasis in primary familial brain calcification. PMID: 25938945
  3. These studies suggest that the expression of Xpr1 and certain genotypes of the RNASEL gene, which could restrict XMRV infection, may play important roles in defining XMRV tropisms in certain cell types. PMID: 20410264
Involvement in disease
Basal ganglia calcification, idiopathic, 6 (IBGC6)
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
SYG1 (TC 2.A.94) family
Tissue Specificity
Widely expressed. Detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas and skeletal muscle.
Database Links

HGNC: 12827

OMIM: 605237

KEGG: hsa:9213

STRING: 9606.ENSP00000356562

UniGene: Hs.227656

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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