XPR1

XPCR 1, also recognized by the names SLC53A1 and SYG1, serves as a crucial phosphate efflux transporter in human cells. Located in the plasma membrane, it meticulously regulates phosphate balance across cell boundaries, playing a key role in maintaining the body's phosphate homeostasis. Abnormal expression or dysfunction of XPCR1 is significantly linked to nervous system disorders, such as primary familial brain calcification and renal Fanconi syndrome. Investigating XPCR1 not only enhances our understanding of these conditions but also holds promise for developing therapeutic strategies. Additionally, XPCR1 is important for cellular metabolism and signal transduction, underscoring its significance in biological and medical research.