XPR1 Antibody

Datasheet

Code	CSB-PA026228GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9UBH6

Target Names

XPR1

Alternative Names

FLJ90308 antibody; OTTHUMP00000033084 antibody; OTTHUMP00000033085 antibody; Polytropic murine leukamia virus receptor SYG 1 antibody; Polytropic murine leukamia virus receptor SYG1 antibody; Protein SYG1 homolog antibody; SYG 1 antibody; SYG1 antibody; SYG1 protein antibody; X-receptor antibody; X3 antibody; Xenotropic and polytropic murine leukemia virus receptor X3 antibody; Xenotropic and polytropic retrovirus receptor antibody; Xenotropic and polytropic retrovirus receptor 1 antibody; XPR 1 antibody; XPR1 antibody; XPR1 protein antibody; XPR1_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human XPR1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Form

Liquid

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules.

Gene References into Functions

These results confirm that loss of XPR1-mediated phosphate export function causes primary familial brain calcification, occurring in less than 8 % of cases negative for the other genes, and may be responsible for parkinsonism. PMID: 27230854
XPR1 mutations alter phosphate export and phosphate homeostasis in primary familial brain calcification. PMID: 25938945
These studies suggest that the expression of Xpr1 and certain genotypes of the RNASEL gene, which could restrict XMRV infection, may play important roles in defining XMRV tropisms in certain cell types. PMID: 20410264

Involvement in disease

Basal ganglia calcification, idiopathic, 6 (IBGC6)

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

SYG1 (TC 2.A.94) family

Tissue Specificity

Widely expressed. Detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas and skeletal muscle.

Database Links

HGNC: 12827

OMIM: 605237

KEGG: hsa:9213

STRING: 9606.ENSP00000356562

UniGene: Hs.227656

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Target Therapy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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