ZIP1 Antibody, FITC conjugated

Code CSB-PA339148LC01SVG
Size US$166
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker\'s yeast) ZIP1 Polyclonal antibody
Uniprot No.
Target Names
ZIP1
Alternative Names
ZIP1 antibody; YDR285W antibody; D9819.9Synaptonemal complex protein ZIP1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae
Immunogen
Recombinant Saccharomyces cerevisiae Synaptonemal complex protein ZIP1 protein (1-227AA)
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker\'s yeast)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for meiotic chromosome synapsis and cell cycle progression. May act as a molecular zipper to bring homologous chromosomes in close apposition. ZIP1 may encode the transverse filaments of the synaptonemal complex.
Gene References into Functions
  1. We discuss a model in which central element proteins are core building blocks that stabilize the architecture of SC near Zip1's N termini PMID: 24098146
  2. Data demonstrate that chromosomes are preloaded with Zip1p in a manner that may promote synapsis. PMID: 20375150
  3. Different functions of Zip1 display differential sensitivities to changes in expression levels. PMID: 19714362
  4. zip1 promotes the segregation of nonexchange chromosomes that are not tethered byp zip1 at centromeres. PMID: 20080752
  5. description of a process in meiotic cells in which chromosomes become joined together in pairs at their centromeres independent of chromosomal homology; these centromeric interactions depend on the synaptonemal complex component Zip1 PMID: 15879219
  6. The zip1-4LA defect in recombination is an indirect consequence of cell cycle arrest. PMID: 17435220
  7. Zip1 and Hop1 Occur with Differential Hyperabundance Along Pachytene Chromosomes; Differential Hop1/Zip1 Hyperabundance Depends on Pch2 PMID: 18305165

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Subcellular Location
Nucleus. Chromosome. Note=Synapsed meiotic chromosomes.
Database Links

KEGG: sce:YDR285W

STRING: 4932.YDR285W

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