ZIP1 Antibody, FITC conjugated

^{Rare Species}

Datasheet

Code	CSB-PA339148LC01SVG
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker\'s yeast) ZIP1 Polyclonal antibody

Uniprot No.

P31111

Target Names

ZIP1

Alternative Names

ZIP1 antibody; YDR285W antibody; D9819.9Synaptonemal complex protein ZIP1 antibody

Raised in

Rabbit

Species Reactivity

Saccharomyces cerevisiae

Immunogen

Recombinant Saccharomyces cerevisiae Synaptonemal complex protein ZIP1 protein (1-227AA)

Immunogen Species

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker\'s yeast)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Required for meiotic chromosome synapsis and cell cycle progression. May act as a molecular zipper to bring homologous chromosomes in close apposition. ZIP1 may encode the transverse filaments of the synaptonemal complex.

Gene References into Functions

We discuss a model in which central element proteins are core building blocks that stabilize the architecture of SC near Zip1's N termini PMID: 24098146
Data demonstrate that chromosomes are preloaded with Zip1p in a manner that may promote synapsis. PMID: 20375150
Different functions of Zip1 display differential sensitivities to changes in expression levels. PMID: 19714362
zip1 promotes the segregation of nonexchange chromosomes that are not tethered byp zip1 at centromeres. PMID: 20080752
description of a process in meiotic cells in which chromosomes become joined together in pairs at their centromeres independent of chromosomal homology; these centromeric interactions depend on the synaptonemal complex component Zip1 PMID: 15879219
The zip1-4LA defect in recombination is an indirect consequence of cell cycle arrest. PMID: 17435220
Zip1 and Hop1 Occur with Differential Hyperabundance Along Pachytene Chromosomes; Differential Hop1/Zip1 Hyperabundance Depends on Pch2 PMID: 18305165

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Subcellular Location

Nucleus. Chromosome. Note=Synapsed meiotic chromosomes.

Database Links

KEGG: sce:YDR285W

STRING: 4932.YDR285W

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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