ZIP1 Antibody

Rare Species
Code CSB-PA339148XA01SVG
Size US$299
Image
  • Western Blot
    Positive WB detected in Recombinant protein
    All lanes: ZIP1 antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 29.2 kDa
    Observed band size: 43 kDa
Promotion Free Antibody trial simple
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Product Details

Uniprot No.
Target Names
ZIP1
Alternative Names
Synaptonemal complex protein ZIP1 ZIP1 YDR285W D9819.9
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ZIP1 protein (603-875aa)
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for meiotic chromosome synapsis and cell cycle progression. May act as a molecular zipper to bring homologous chromosomes in close apposition. ZIP1 may encode the transverse filaments of the synaptonemal complex.
Gene References into Functions
  1. We discuss a model in which central element proteins are core building blocks that stabilize the architecture of SC near Zip1's N termini PMID: 24098146
  2. Data demonstrate that chromosomes are preloaded with Zip1p in a manner that may promote synapsis. PMID: 20375150
  3. Different functions of Zip1 display differential sensitivities to changes in expression levels. PMID: 19714362
  4. zip1 promotes the segregation of nonexchange chromosomes that are not tethered byp zip1 at centromeres. PMID: 20080752
  5. description of a process in meiotic cells in which chromosomes become joined together in pairs at their centromeres independent of chromosomal homology; these centromeric interactions depend on the synaptonemal complex component Zip1 PMID: 15879219
  6. The zip1-4LA defect in recombination is an indirect consequence of cell cycle arrest. PMID: 17435220
  7. Zip1 and Hop1 Occur with Differential Hyperabundance Along Pachytene Chromosomes; Differential Hop1/Zip1 Hyperabundance Depends on Pch2 PMID: 18305165

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Subcellular Location
Nucleus. Chromosome. Note=Synapsed meiotic chromosomes.
Database Links

KEGG: sce:YDR285W

STRING: 4932.YDR285W

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