ZKSCAN4 Antibody

Code CSB-PA005456
Size US$100
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  • Western Blot analysis of MCF7 HepG2 293 mouse brain mouse lung cells using ZKSCAN4 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
ZKSCAN4
Alternative Names
FLJ32136 antibody; P1P373C6 antibody; p373c6.1 (novel C2H2 type zinc finger protein) antibody; P373c6.1 antibody; Zinc finger protein 307 antibody; Zinc finger protein 427 antibody; Zinc finger protein with KRAB and SCAN domains 4 antibody; Zinc finger with KRAB and SCAN domains 4 antibody; ZKSC4_HUMAN antibody; ZKSCAN4 antibody; ZNF427 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human ZKSCAN4.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in the transcriptional activation of MDM2 and EP300 genes.
Gene References into Functions
  1. our results indicate that ZNF307 may serve as a tumor suppressor and inhibits cell proliferation of hepatocellular carcinoma via inducing apoptosis PMID: 28765950
  2. ZNF307 ameliorates pressure overload-induced cardiac hypertrophy by inhibiting the activity of NF-kappaB-signaling pathway PMID: 28223477
  3. ZNF307 might suppress p53-p21 pathway through activating MDM2 and EP300 expression and inducing p53 degradation PMID: 17910948
  4. The SCAN- and KRAB-domain-containing zinc finger protein 307 (ZKSCAN4) was co-precipitated with the receptor when both proteins were overexpressed in HEK293 cells. PMID: 19008334
Subcellular Location
Nucleus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Tissue Specificity
Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.
Database Links

HGNC: 13854

OMIM: 611643

KEGG: hsa:387032

STRING: 9606.ENSP00000366509

UniGene: Hs.44720

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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