ZNF274 Antibody, HRP conjugated

Code CSB-PA850299LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZNF274 Polyclonal antibody
Uniprot No.
Target Names
ZNF274
Alternative Names
ZNF274 antibody; ZKSCAN19 antibody; SP2114Neurotrophin receptor-interacting factor homolog antibody; Zinc finger protein 274 antibody; Zinc finger protein HFB101 antibody; Zinc finger protein with KRAB and SCAN domains 19 antibody; Zinc finger protein zfp2 antibody; Zf2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Neurotrophin receptor-interacting factor homolog protein (1-320AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc-finger coding genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions.
Gene References into Functions
  1. A proximal promoter construct for the MAS gene was repressed by the SOX [SRY (sex-determining region on the Y chromosome) box] proteins SRY, SOX2, SOX3 and SOX14, of which SRY is known to interact with the KRAB domain. PMID: 24128372
Subcellular Location
Cytoplasm. Nucleus, nucleolus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Database Links

HGNC: 13068

OMIM: 605467

KEGG: hsa:10782

STRING: 9606.ENSP00000321209

UniGene: Hs.83761

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