ZNF420 Antibody, Biotin conjugated

Code CSB-PA026737LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZNF420 Polyclonal antibody
Uniprot No.
Target Names
ZNF420
Alternative Names
ZNF420 antibody; Zinc finger protein 420 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Zinc finger protein 420 protein (50-256AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in transcriptional regulation.
Gene References into Functions
  1. Functional importance of H3K9me3 in hypoxia, apoptosis and repression of APAK. PMID: 25961932
  2. ARF coordinates Apak to regulate ribosome biogenesis upon cellular stress. PMID: 25691462
  3. Apak is differentially regulated in the ARF and ATM-dependent manner in response to oncogenic stress and DNA damage, respectively. PMID: 20713054
  4. four of seven types of DNA damage signals examined resulted in significant Apak phosphorylation and dissociation of Apak from p53, releasing the inhibition of p53 transcriptional activity PMID: 19629643
  5. Apak (ZNF420 or FLJ32191) is a negative regulator of p53-mediated apoptosis. PMID: 19377469

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Subcellular Location
Nucleus.
Database Links

HGNC: 20649

KEGG: hsa:147923

STRING: 9606.ENSP00000338770

UniGene: Hs.444992

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