ZNF420 Antibody

Code CSB-PA570335
Size US$297
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  • Western blot analysis of extracts from K562 cells, using ZNF420 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZNF420 Polyclonal antibody
Uniprot No.
Target Names
ZNF420
Alternative Names
ZNF420 antibody; Zinc finger protein 420 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human ZNF420.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in transcriptional regulation.
Gene References into Functions
  1. Functional importance of H3K9me3 in hypoxia, apoptosis and repression of APAK. PMID: 25961932
  2. ARF coordinates Apak to regulate ribosome biogenesis upon cellular stress. PMID: 25691462
  3. Apak is differentially regulated in the ARF and ATM-dependent manner in response to oncogenic stress and DNA damage, respectively. PMID: 20713054
  4. four of seven types of DNA damage signals examined resulted in significant Apak phosphorylation and dissociation of Apak from p53, releasing the inhibition of p53 transcriptional activity PMID: 19629643
  5. Apak (ZNF420 or FLJ32191) is a negative regulator of p53-mediated apoptosis. PMID: 19377469

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Subcellular Location
Nucleus.
Database Links

HGNC: 20649

KEGG: hsa:147923

STRING: 9606.ENSP00000338770

UniGene: Hs.444992

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