ZNF420 Antibody, FITC conjugated

Code CSB-PA026737LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZNF420 Polyclonal antibody
Uniprot No.
Target Names
ZNF420
Alternative Names
ZNF420 antibody; Zinc finger protein 420 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Zinc finger protein 420 protein (50-256AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May be involved in transcriptional regulation.
Gene References into Functions
  1. Functional importance of H3K9me3 in hypoxia, apoptosis and repression of APAK. PMID: 25961932
  2. ARF coordinates Apak to regulate ribosome biogenesis upon cellular stress. PMID: 25691462
  3. Apak is differentially regulated in the ARF and ATM-dependent manner in response to oncogenic stress and DNA damage, respectively. PMID: 20713054
  4. four of seven types of DNA damage signals examined resulted in significant Apak phosphorylation and dissociation of Apak from p53, releasing the inhibition of p53 transcriptional activity PMID: 19629643
  5. Apak (ZNF420 or FLJ32191) is a negative regulator of p53-mediated apoptosis. PMID: 19377469

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Subcellular Location
Nucleus.
Database Links

HGNC: 20649

KEGG: hsa:147923

STRING: 9606.ENSP00000338770

UniGene: Hs.444992

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