ZPR1 Antibody

1. Results suggest that ZPR1 plays an important role in the etiology of type 2 diabetes mellitus, and this gene might be involved in abnormal glucose metabolism. PMID: 27411854
2. When the inter-dependence between alleles was examined using conditional models, five loci on BUD13, ZNF259, and ApoA5 showed possible independent associations. PMID: 26634697
3. Single nucleotide polymorphisms (Rs964184, rs3317316, rs6589566) of ZNF259 protein did not increase the risk of CHD in the Chinese population. PMID: 26397108
4. ZNF259 variants were associated with elevated Metabolic Syndrome risk in a Han Chinese population from the Jilin province of Northeastern China PMID: 26118197
5. Single nucleotide polymorphism zinc finger protein 259 gene is associated with hyperlipidaemia. PMID: 24780069
6. Significant linkage disequilibria were noted among ZNF259, BUD13 and MLXIPL SNPs and serum lipid levels. PMID: 24989072
7. These findings suggest that the association between ZNF259 rs2075290 SNP and serum lipid levels might have ethnic- and/or sex-specificity. PMID: 24688311
8. Novel APOA5-ZNF259 haplotype manifesting sex-dependent effects on elevation of the TG:HDL-C ratio as well as the increased risk for metabolic syndrome. PMID: 24618354
9. genetic polymorphism at the loci is associated with Factor VII and fibrinogen levels, and with plasma viscosity PMID: 24178511
10. Significant associations of two SNPs (rs964184 and rs12286037) from ZNF259 with triglyceride levels in an Asian Indian cohort. PMID: 22623978
11. ZPR1 deficiency causes disruption of survival motor neurons and histone gene-specific transcription factor NPAT localization within the nucleus, blocks S phase progression, and arrests cells in both the G1 and G2 phases of the cell cycle. PMID: 17068332

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HGNC: 13051

OMIM: 603901

KEGG: hsa:8882

STRING: 9606.ENSP00000227322

UniGene: Hs.7165