ply Antibody, Biotin conjugated

Code CSB-PA314690HD01FMW
Size US$166
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Product Details

Full Product Name
Rabbit anti-Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) ply Polyclonal antibody
Uniprot No.
Target Names
ply
Alternative Names
ply antibody; SP_1923 antibody; Pneumolysin antibody; Ply antibody; Thiol-activated cytolysin antibody
Raised in
Rabbit
Species Reactivity
Streptococcus pneumoniae serotype 4
Immunogen
Recombinant Streptococcus pneumoniae serotype 4 Pneumolysin protein (2-471AA)
Immunogen Species
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol is required for binding to host membranes, membrane insertion and pore formation; cholesterol binding is mediated by a Thr-Leu pair in the C-terminus. Can be reversibly inactivated by oxidation.
Subcellular Location
Secreted. Secreted, cell wall. Host cell membrane; Multi-pass membrane protein.
Protein Families
Thiol-activated cytolysin family
Database Links

KEGG: spn:SP_1923

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