tir Antibody

Datasheet

Code	CSB-PA514896HA01EOF
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Escherichia coli O157:H7 (strain TW14359 / EHEC) tir Polyclonal antibody

Uniprot No.

C6UYL8

Target Names

tir

Alternative Names

tir antibody; espE antibody; ECSP_4676 antibody; Translocated intimin receptor Tir antibody; Secreted effector protein Tir antibody

Raised in

Rabbit

Species Reactivity

Escherichia coli O157:H7

Immunogen

Recombinant Escherichia coli O157:H7 Translocated intimin receptor Tir protein (252-362AA)

Immunogen Species

Escherichia coli O157:H7 (strain TW14359 / EHEC)

Conjugate

Non-conjugated

The tir Antibody (Product code: CSB-PA514896HA01EOF) is Non-conjugated. For tir Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA514896HB01EOF	tir Antibody, HRP conjugated	ELISA
FITC	CSB-PA514896HC01EOF	tir Antibody, FITC conjugated
Biotin	CSB-PA514896HD01EOF	tir Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion.

Subcellular Location

Secreted. Host cell membrane; Multi-pass membrane protein.

Protein Families

Tir receptor family

Database Links

KEGG: etw:ECSP_4676

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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