tir Antibody, Biotin conjugated

Rare Species
Code CSB-PA514896HD01EOF
Size US$166
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Product Details

Full Product Name
Rabbit anti-Escherichia coli O157:H7 (strain TW14359 / EHEC) tir Polyclonal antibody
Uniprot No.
Target Names
tir
Alternative Names
tir antibody; espE antibody; ECSP_4676 antibody; Translocated intimin receptor Tir antibody; Secreted effector protein Tir antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli O157:H7
Immunogen
Recombinant Escherichia coli O157:H7 Translocated intimin receptor Tir protein (252-362AA)
Immunogen Species
Escherichia coli O157:H7 (strain TW14359 / EHEC)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion.
Subcellular Location
Secreted. Host cell membrane; Multi-pass membrane protein.
Protein Families
Tir receptor family
Database Links
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