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| Code | CSB-EP011718BO |
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| Size | US$388 |
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Recombinant Bovine INHA protein is an E.coli-expressed protein (Full Length of Mature Protein). Molecularly, this INHA protein is characterized by N-terminal 6xHis-SUMO tag, internal Bovine INHA DNA fragment (227-360aa). Standard methods for recombinant INHA protein expression comprise transfecting cells with DNA vectors that consist of specific templates and then cultures cells to translate and transcribe the INHA protein production process. Typically, these cells are lysed to extract expressed proteins for more purification. The purity of this recombinant INHA protein is 90%+ measured by SDS-PAGE.
INHA is the alpha subunit of inhibin, the inhibitor of the synthesis and secretion of pituitary gonadotropins, especially follicle-stimulating hormone (FSH). INHA has recently been involved in prostate tumorigenesis. It is overexpressed in mice, leading to aberrant reproductive function, including reduced litter and embryo size. INHA expression was declined in early-stage tumors but elevated in late-stage, metastatic prostate malignancies, implying that inhibins function as tumor inhibitors in the early stage of carcinogenesis but may serve as tumor promoters during late-stage disease.
Applications : immunization assay
Review: Ovarian follicular activity of dromedary camels (n=5) actively-immunized against recombinant bovine inhibin-A during the transition period (mid-August to mid- December)
By Anonymous
