Product Details

Purity

Greater than 90% as determined by SDS-PAGE.

Target Names

PTX3

Uniprot No.

Q0VCG9

Research Area

Others

Alternative Names

PTX3; Pentraxin-related protein PTX3; Pentaxin-related protein PTX3

Species

Bos taurus (Bovine)

Source

Mammalian cell

Expression Region

18-382aa

Target Protein Sequence

ENSDDYELMYVNLDNEIDNGLHPTEDPTPCDCSRENSEWDKLFTMLENSQMREGMLLQATDVMLRGELQKLQAELGRLEGSLQKLCGPEAPSETRLARALDDLLQASRDAGRRLARLEDAGALRPQEEAGRALGAVLEELRRTRADLRAVQGWAASRWLPAGCETAILFPMRSKKIFASVHPVTPMKLETFSACIWVKATEVLNKTVLFSYGTKRNPYEIQLYLSYRSIMLVVGGEENRLVADAVISLGTWTHLCSTWDSKKGHMALWVNGDSVATAVDMATGHVVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWEGVLSNEEIREAGGAESCHIRGNVVGWGVTEIQPHGGAQYVY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Mol. Weight

44.7 kDa

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal Flag-Myc-tagged

Form

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet & COA

Please contact us to get it.

Description

Recombinant Bovine PTX3 protein is a mammalian cell-expressed protein (Full Length of Mature Protein). Molecularly, this PTX3 protein is characterized by N-terminal Flag-Myc tag, and an internal Bovine PTX3 DNA fragment, 18-382aa. Its purity is 90%+ measured by SDS-PAGE. This recombinant production is the biotechnological process of generating a specific protein, and the host cell that we use are HEK293 cells. The Mammalian cell expression system can provide the most complete glycosylation, such as the complex N-type glycosylation and accurate O-glycosylation modifications, usually, the protein expressed by the mammalian cell system is closest to the conformation of the natural protein.

PTX3 is a protein coding gene that encodes Pentraxin-related protein PTX3. According to some research, PTX3 may have the following features.
The long pentraxin Ptx3 is a secreted pattern recognition receptor with a non-redundant role in resistance to selected microbial agents. PTX3 is a useful new serological marker that rapidly reflects tissue inflammation and damage in different clinical conditions. PTX3 binds to P-selectin and attenuates neutrophil recruitment to sites of inflammation. The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localized in extracellular traps. PTX3 is an extrinsic tumor suppressor that regulates complement-dependent inflammation in cancer.

Target Background

Function

Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.

Gene References into Functions

there is an FGF2-binding domain in the N-terminal extension of PTX3 spanning the PTX3-(97-110) region PMID: 16769728

Subcellular Location

Secreted.

Database Links

KEGG: bta:541148

STRING: 9913.ENSBTAP00000011863

UniGene: Bt.7541

Code	CSB-MP610820BO
Abbreviation	Recombinant Bovine PTX3 protein
MSDS	MSDS Datasheet
Size	$440
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Image	(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Recombinant Bovine Pentraxin-related protein PTX3 (PTX3)

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