Recombinant Bovine Pentraxin-related protein PTX3 (PTX3)

Recombinant Bovine PTX3 protein is a mammalian cell-expressed protein (Full Length of Mature Protein). Molecularly, this PTX3 protein is characterized by N-terminal Flag-Myc tag, and an internal Bovine PTX3 DNA fragment, 18-382aa. Its purity is 90%+ measured by SDS-PAGE. This recombinant production is the biotechnological process of generating a specific protein, and the host cell that we use are HEK293 cells. The Mammalian cell expression system can provide the most complete glycosylation, such as the complex N-type glycosylation and accurate O-glycosylation modifications, usually, the protein expressed by the mammalian cell system is closest to the conformation of the natural protein.

PTX3 is a protein coding gene that encodes Pentraxin-related protein PTX3. According to some research, PTX3 may have the following features.
The long pentraxin Ptx3 is a secreted pattern recognition receptor with a non-redundant role in resistance to selected microbial agents. PTX3 is a useful new serological marker that rapidly reflects tissue inflammation and damage in different clinical conditions. PTX3 binds to P-selectin and attenuates neutrophil recruitment to sites of inflammation. The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localized in extracellular traps. PTX3 is an extrinsic tumor suppressor that regulates complement-dependent inflammation in cancer.