Recombinant Chicken Interferon regulatory factor 1(IRF1)

Code CSB-YP011814CH
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Source Yeast
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Code CSB-EP011814CH
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Source E.coli
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Code CSB-EP011814CH-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP011814CH
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Source Baculovirus
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Code CSB-MP011814CH
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names IRF1
Uniprot No. Q90876
Alternative Names IRF1Interferon regulatory factor 1; IRF-1
Species Gallus gallus (Chicken)
Expression Region 1-313
Target Protein Sequence MPVSRMRMRP WLEMQINSNQ IPGLIWINKD KMIFQIPWKH AAKHGWDMEK DACLFRSWAI HTGRYKVGEK DPDPKTWKAN FRCAMNSLPD IEEVKDKSIN KGSSAVRVYR MLPPLTKDQK KERKSKSSRE ARNKSKRKLY EDMRMEESAE RLTSTPLPDD HSSYTAHDYT GQEVEVENTS ITLDLSSCEV SGSLTDWRMP MEIAMADSTN DIYQLQVSPL GSSSEDEDEM KSNIIKLLEP TQDWHTTSVE GKGFFTNEPG TQTMCSTFGY KEQDGEIDTS SAELEFRMMD QKSSLDFSWL DTVRPMQAIS CSL
Protein Length full length protein
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Background

Function
Transcriptional regulator that specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor.
Gene References into Functions
  1. these studies demonstrate that chIRF1 is an important regulator of IFN-beta and is involved in chicken antiviral innate immunity. PMID: 29981306
Subcellular Location Nucleus. Cytoplasm.
Protein Families IRF family
Database Links

KEGG: gga:396384

STRING: 9031.ENSGALP00000002242

UniGene: Gga.791

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
Address
7505 Fannin St. Ste 610-312, Houston, TX 77054, USA
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