Recombinant Chicken Prospero homeobox protein 1(PROX1) ,partial

Code CSB-YP820911CH
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Source Yeast
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Code CSB-EP820911CH
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Source E.coli
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Code CSB-EP820911CH-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP820911CH
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Source Baculovirus
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Code CSB-MP820911CH
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names PROX1
Uniprot No. Q91018
Alternative Names PROX1; Prospero homeobox protein 1; Homeobox prospero-like protein PROX1; PROX-1
Species Gallus gallus (Chicken)
Protein Length Partial
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Data

Function Transcription factor which may be involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. May be essential in the development and function of the eye. May play a role in the regulation of the circadian rhythm by repressing the expression of clock genes.
Gene References into Functions
  1. We show that b-catenin is expressed during the pre-patterning of the epithelium prior to papilla induction and second that b-catenin, Ednrb and Inhba are expressed during the induction and patterning of the conjunctival papillae. Furthermore, we identified two genes, b-catenin and Prox1, that may be involved in the induction of the underlying scleral bones PMID: 27664768
  2. Results define the neurogenesis period in the chick paravertebral sympathetic ganglia including an initial cell cycle withdrawal and identify Prox1 as a marker and regulator of proliferating sympathetic neuroblasts PMID: 25788138
  3. Results showed that VEGF-A/HGF combination was able to induce a strong angiogenic response and the expression of Prox-1 in the lymphatic endothelial cells of the chick embryo chorioallantoic membrane. PMID: 20033752
  4. Data show that Prox1 is expressed in embryonic sympathetic trunk ganglia of avian and murine embryos. PMID: 20453716
  5. These data suggest that Prox1 function as a transcriptional activator could be regulated at the DNA level based on the characteristics of the responsive elements. PMID: 18385074

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Subcellular Location Nucleus
Protein Families Prospero homeodomain family
Tissue Specificity Expressed most actively in the developing lens and midgut and at lower levels in the developing brain, heart, muscle and retina.
Database Links

KEGG: gga:395802

STRING: 9031.ENSGALP00000015911

UniGene: Gga.2460

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