Recombinant Danio rerio Insulin gene enhancer protein isl-2a (isl2a)

Code CSB-YP346859DIL
MSDS
Size Pls inquire
Source Yeast
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-EP346859DIL
MSDS
Size Pls inquire
Source E.coli
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-EP346859DIL-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-BP346859DIL
MSDS
Size Pls inquire
Source Baculovirus
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-MP346859DIL
MSDS
Size Pls inquire
Source Mammalian cell
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Purity
>85% (SDS-PAGE)
Target Names
isl2a
Uniprot No.
Alternative Names
isl2a; isl-2; isl2; Insulin gene enhancer protein isl-2a; Islet-2A; Insulin gene enhancer protein isl-2; Islet-2
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Expression Region
1-359
Target Protein Sequence
MVDILPHPSF LGDMGDHSKK KSGIAMCVGC GSQIHDQYIL RVSPDLEWHA ACLKCAECSQ YLDETCTCFV RDGKTYCKRD YVRLFGIKCA KCNIGFCSSD LVMRARDNVY HMECFRCSVC SRHLLPGDEF SLRDEELLCR ADHGLLMERA SAGSPISPGN IHSSRPLHIP EPVPVRQPPH RNHVHKQSEK TTRVRTVLNE KQLHTLRTCY NANPRPDALM KEQLVEMTGL SPRVIRVWFQ NKRCKDKKKS ILMKQLQQQQ HNDKTNLQGL TGTPLVAGSP IRHDTTVQGN PVEVQTYQPP WKALSEFALQ SDLDQPAFQQ LVSFSESGSL GNSSGSDVTS LSSQLPDTPN SMVPSPVET
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Binds to one of the cis-acting domain of the insulin gene enhancer. May be involved in subtype specialization of primary motoneurons.
Gene References into Functions
  1. Isl2a is expressed in the lateral posterior mesoderm prior to angioblast migration. Isl2a-deficient angioblasts show disorganized migration to the midline to form axial vessels. Its expression is negatively regulated by Notch activity. It positively regulates flt4, a VEGF-C receptor repressed by Notch during angiogenesis. Isl2a may be an intermediate between Notch signaling and genetic programs controlling angioblasts. PMID: 27126199
  2. Prdm14 regulates caudal rimary axon outgrowth through activation of islet2 expression. PMID: 23136389
  3. Results show that PlexinA4, a transmembrane protein known to be a co-receptor for class III semaphorins, acts downstream of Islet2 to promote branching of the peripheral axons of the primary sensory neurons. PMID: 15229183
Subcellular Location
Nucleus.
Database Links

KEGG: dre:30157

STRING: 7955.ENSDARP00000020636

UniGene: Dr.281

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1