Recombinant Goat Interleukin-4(IL4)

Product Type Recombinant Protein
Uniprot No. P79155
Species Capra hircus (Goat)
Gene Names IL4
Protein Names Recommended name: Interleukin-4 Short name= IL-4 Alternative name(s): B-cell stimulatory factor 1 Short name= BSF-1 Lymphocyte stimulatory factor 1
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This protein is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
HGNC 6014
RGD 2898
MGI 96556
Function Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.
Subcellular Location Secreted
Protein Families IL-4/IL-13 family
Database Links

KEGG: chx:100860814

UniGene: Chi.38713

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Fc epsilon RI signaling pathway
Hematopoietic cell lineage
IL-17 signaling pathway
T cell receptor signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation

Product Details for Different Expression Systems

Product Name Recombinant Goat Interleukin-4(IL4),Yeast
Code CSB-YP011659GO
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence HKCDIT LEEIIKMLNI LTSQKNSCME LPVADVFAAP KNATEKETFC RAGIELRRIY RNHMCLNKFL GGLDRNLSSL ASKTCSVNEA KTSTSTLRDL LERLKTIMKE KYSKC
Expression Region 25-135
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Goat Interleukin-4(IL4),E.coli
Code CSB-EP011659GO
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence HKCDIT LEEIIKMLNI LTSQKNSCME LPVADVFAAP KNATEKETFC RAGIELRRIY RNHMCLNKFL GGLDRNLSSL ASKTCSVNEA KTSTSTLRDL LERLKTIMKE KYSKC
Expression Region 25-135
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Goat Interleukin-4(IL4),Baculovirus
Code CSB-BP011659GO
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence HKCDIT LEEIIKMLNI LTSQKNSCME LPVADVFAAP KNATEKETFC RAGIELRRIY RNHMCLNKFL GGLDRNLSSL ASKTCSVNEA KTSTSTLRDL LERLKTIMKE KYSKC
Expression Region 25-135
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Goat Interleukin-4(IL4),Mammalian cell
Code CSB-MP011659GO
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence HKCDIT LEEIIKMLNI LTSQKNSCME LPVADVFAAP KNATEKETFC RAGIELRRIY RNHMCLNKFL GGLDRNLSSL ASKTCSVNEA KTSTSTLRDL LERLKTIMKE KYSKC
Expression Region 25-135
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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