Recombinant Human Arf-GAP with dual PH domain-containing protein 1(ADAP1)

Code CSB-EP001322HU
Product Type Recombinant Protein
Size US$1726
Uniprot No. O75689
Relevance GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias Centaurin-alpha-1
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP
Research Area Microbiology
Source E.coli
Gene Names ADAP1
Protein Names Recommended name: Arf-GAP with dual PH domain-containing protein 1 Alternative name(s): Centaurin-alpha-1 Short name= Cnt-a1 Putative MAPK-activating protein PM25
Expression Region 1-374aa
Tag Info N-terminal GST-tagged
Mol. Weight 70.4kDa
Protein Description Full Length of BC033747
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).
Subcellular Location Nucleus, Cytoplasm
Tissue Specificity Expressed at highest levels in brain and at lower levels in peripheral blood leukocytes.
Database Links

HGNC: 16486

OMIM: 608114

KEGG: hsa:11033

STRING: 9606.ENSP00000265846

UniGene: Hs.602573

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