Recombinant Human Beta-1,4-galactosyltransferase 5(B4GALT5),partial

Code CSB-YP527356HU
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Source Yeast
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Code CSB-EP527356HU
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Source E.coli
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Code CSB-EP527356HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP527356HU
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Source Baculovirus
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Code CSB-MP527356HU
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names B4GALT5
Uniprot No. O43286
Alternative Names 4-galactosyltransferase 5; 4-GalT II; 4-GalTase 5; B4Gal T5; b4Gal-T5; B4galt5; B4GT5_HUMAN; Beta 1 4 galactosyltransferase 5; Beta 1 4 galactosyltransferase V; Beta 1 4 GalT II; Beta 1 4 GalT IV; Beta 1 4 GalTase 5; Beta-1; Beta-1,4-galactosyltransferase 5; Beta-1,4-GalT II; Beta-1,4-GalTase 5; Beta4 GALT IV; Beta4Gal T5; Beta4Gal-T5; Beta4GalT V; gt V; gtV; MGC138470; UDP Gal:beta GlcNAc beta 1 4 galactosyltransferase 5; UDP Gal:betaGlcNAc beta 1 4 galactosyltransferase 5; UDP Gal:betaGlcNAc beta 1 4 galactosyltransferase polypeptide 5; UDP galactose:beta N acetylglucosamine beta 1 4 galactosyltransferase 5; UDP-Gal:beta-GlcNAc beta-1; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5
Species Homo sapiens (Human)
Protein Length Partial
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Data

Function Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.
Gene References into Functions
  1. 2.3-kb 5'-flanking region of the human beta-1,4-GalT V gene was cloned and the region -116/-18 relative to the transcription start site as that having promoter activity. PMID: 15263012
  2. B4GALT1 and B4GALT5, two members of B4GALT gene family, are involved in the development of multidrug resistance of human leukemia cells. PMID: 23744354
  3. The expression of the beta-1,4-GalT V gene has been shown to be regulated by transcription factors Sp1 and Ets-1 in cancer cells.(review) PMID: 22687727
  4. These data reveal a critical role of beta1,4GalT V in the self-renewal and tumorigenicity of glioma-initiating cells. PMID: 20417617
  5. Over-expression of beta-1,4-galactosyltransferase V increases the growth of astrocytoma cell line PMID: 12385586
  6. results suggest that GalT V functioned as a novel glioma growth activator and might represent a novel target in glioma therapy PMID: 16461357
  7. Ets-1 enhances expression of the beta-1,4-GalT V gene through activation of the Sp1 gene in cancer cells PMID: 17656364

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Subcellular Location Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein
Protein Families Glycosyltransferase 7 family
Tissue Specificity Ubiquitously expressed.
Database Links

HGNC: 928

OMIM: 604016

KEGG: hsa:9334

STRING: 9606.ENSP00000360776

UniGene: Hs.370487

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