B4GALT5 Antibody

Datasheet

Citations (1)

Code	CSB-PA527356LA01HU
Size	US$166
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Image	Western Blot All lanes: B4GALT5 antibody at 8µg/ml Lane 1: Mouse heart tissue Lane 2: Mouse liver tissue Lane 3: Mouse brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 46 kDa Observed band size: 46 kDa Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA527356LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA527356LA01HU at dilution of 1:100
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Product Details
Citations
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) B4GALT5 Polyclonal antibody

Uniprot No.

O43286

Target Names

B4GALT5

Alternative Names

4-galactosyltransferase 5 antibody; 4-GalT II antibody; 4-GalTase 5 antibody; B4Gal T5 antibody; b4Gal-T5 antibody; B4galt5 antibody; B4GT5_HUMAN antibody; Beta 1 4 galactosyltransferase 5 antibody; Beta 1 4 galactosyltransferase V antibody; Beta 1 4 GalT II antibody; Beta 1 4 GalT IV antibody; Beta 1 4 GalTase 5 antibody; Beta-1 antibody; Beta-1,4-galactosyltransferase 5 antibody; Beta-1,4-GalT II antibody; Beta-1,4-GalTase 5 antibody; Beta4 GALT IV antibody; Beta4Gal T5 antibody; Beta4Gal-T5 antibody; Beta4GalT V antibody; gt V antibody; gtV antibody; MGC138470 antibody; UDP Gal:beta GlcNAc beta 1 4 galactosyltransferase 5 antibody; UDP Gal:betaGlcNAc beta 1 4 galactosyltransferase 5 antibody; UDP Gal:betaGlcNAc beta 1 4 galactosyltransferase polypeptide 5 antibody; UDP galactose:beta N acetylglucosamine beta 1 4 galactosyltransferase 5 antibody; UDP-Gal:beta-GlcNAc beta-1 antibody; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5 antibody; UDP-galactose:beta-N-acetylglucosamine beta-1 antibody; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Beta-1,4-galactosyltransferase 5 protein (101-388AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The B4GALT5 Antibody (Product code: CSB-PA527356LA01HU) is Non-conjugated. For B4GALT5 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA527356LB01HU	B4GALT5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA527356LC01HU	B4GALT5 Antibody, FITC conjugated
Biotin	CSB-PA527356LD01HU	B4GALT5 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

CDK7 blockade suppresses super‐enhancer‐associated oncogenes in bladder cancer Y Yang,Cellular Oncology,2021

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis.

Gene References into Functions

2.3-kb 5'-flanking region of the human beta-1,4-GalT V gene was cloned and the region -116/-18 relative to the transcription start site as that having promoter activity. PMID: 15263012
B4GALT1 and B4GALT5, two members of B4GALT gene family, are involved in the development of multidrug resistance of human leukemia cells. PMID: 23744354
The expression of the beta-1,4-GalT V gene has been shown to be regulated by transcription factors Sp1 and Ets-1 in cancer cells.(review) PMID: 22687727
These data reveal a critical role of beta1,4GalT V in the self-renewal and tumorigenicity of glioma-initiating cells. PMID: 20417617
Over-expression of beta-1,4-galactosyltransferase V increases the growth of astrocytoma cell line PMID: 12385586
results suggest that GalT V functioned as a novel glioma growth activator and might represent a novel target in glioma therapy PMID: 16461357
Ets-1 enhances expression of the beta-1,4-GalT V gene through activation of the Sp1 gene in cancer cells PMID: 17656364

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Subcellular Location

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Golgi apparatus.

Protein Families

Glycosyltransferase 7 family

Tissue Specificity

Ubiquitously expressed.

Database Links

HGNC: 928

OMIM: 604016

KEGG: hsa:9334

STRING: 9606.ENSP00000360776

UniGene: Hs.370487

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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