Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 7 (CEACAM7)

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Code CSB-EP005167HU
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Size $224
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  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Product Details

Purity
Greater than 90% as determined by SDS-PAGE.
Target Names
CEACAM7
Uniprot No.
Research Area
Tags & Cell Markers
Alternative Names
Carcinoembryonic antigen CGM 2; Carcinoembryonic antigen CGM2; Carcinoembryonic antigen gene family member 2; Carcinoembryonic antigen related cell adhesion molecule 7; Carcinoembryonic antigen-related cell adhesion molecule 7; CEA; CEACAM 7; CEACAM7; CEAM7_HUMAN; CGM 2; CGM2
Species
Homo sapiens (Human)
Source
E.coli
Expression Region
36-242aa
Target Protein Sequence
TNIDVVPFNVAEGKEVLLVVHNESQNLYGYNWYKGERVHANYRIIGYVKNISQENAPGPAHNGRETIYPNGTLLIQNVTHNDAGIYTLHVIKENLVNEEVTRQFYVFSEPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGASRSDPVTLNVRYESVQAS
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Mol. Weight
39.4kDa
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal 6xHis-SUMO-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer
Tris-based buffer,50% glycerol
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
3-7 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
Description

Our Recombinant Human CEACAM7 protein is a high-quality and reliable tool for research involving tags and cell markers. This protein, representing the Carcinoembryonic antigen-related cell adhesion molecule 7 (CEACAM7), is crucial for cellular adhesion, migration, and signal transduction. The product is expressed in E. coli, encompassing the full length of the mature CEACAM7 protein (36-242aa), and is tagged with an N-terminal 6xHis-SUMO for ease of purification and detection.

With a purity greater than 90% as determined by SDS-PAGE, our Recombinant Human CEACAM7 protein is provided as a lyophilized powder, ensuring consistent and dependable performance for your tags and cell markers research. This product allows you to achieve precise and reliable results in various research areas, including cancer biology, inflammation, and immune response.

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Target Background

Gene References into Functions
  1. CEACAM7 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
  2. crystal structure of the N-terminal dimerization domain of CEACAM has been determined at 1.47 A resolution PMID: 26323304
  3. High CEACAM7 is associated with gastric carcinoma. PMID: 22195770
  4. CEACAM-7 expression is significantly decreased in rectal cancer; a potential tumor marker PMID: 20004437
  5. CGM2 RT-PCR assay provides no specific prognostic information and cannot be used as a decision criterion for adjuvant therapy after colorectal cancer surgery. PMID: 16627067

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Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane.
Protein Families
Immunoglobulin superfamily, CEA family
Tissue Specificity
Expressed in columnar epithelial cells of the colon (at protein level). Strongly down-regulated in colonic adenocarcinomas.
Database Links

HGNC: 1819

KEGG: hsa:1087

STRING: 9606.ENSP00000006724

UniGene: Hs.74466

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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