Recombinant Human Cystatin-SA (CST2)

Code CSB-YP006090HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP006090HU
MSDS
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Source E.coli
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Code CSB-EP006090HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP006090HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP006090HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
CST2
Uniprot No.
Alternative Names
CST 2; CST2; Cystatin 2; Cystatin S5; Cystatin-2; Cystatin-S5; Cystatin-SA; Cysteine proteinase inhibitor; CYTT_HUMAN; MGC71924; Salivary cysteine (thiol) protease inhibitor
Species
Homo sapiens (Human)
Expression Region
21-141
Target Protein Sequence
WSPQEEDRII EGGIYDADLN DERVQRALHF VISEYNKATE DEYYRRLLRV LRAREQIVGG VNYFFDIEVG RTICTKSQPN LDTCAFHEQP ELQKKQLCSF QIYEVPWEDR MSLVNSRCQE A
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Thiol protease inhibitor.
Gene References into Functions
  1. This data suggests an autoimmune mechanism behind chronic mucocutaneous candidiasis in autoimmune polyendocrine syndrome type I and provides rationale for evaluating cystatin SA1 in antifungal therapy. PMID: 23122533
  2. Identification of cystatin SA as a novel inhibitor of acid ceramidase. PMID: 21846728
  3. cystatins SA1 and SA2 adhere to human fibroblasts and that the event results in tyrosine phosphorylation and upregulation of the release of IL-6 mediated enhancement of NF-kappa B activity. PMID: 12413693
Subcellular Location
Secreted.
Protein Families
Cystatin family
Tissue Specificity
Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in submandibular gland and parotid gland.
Database Links

HGNC: 2474

OMIM: 123856

KEGG: hsa:1470

STRING: 9606.ENSP00000307540

UniGene: Hs.669305

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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