Recombinant Human Cytoplasmic phosphatidylinositol transfer protein 1 (PITPNC1)

Code CSB-YP892330HU
MSDS
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Source Yeast
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Code CSB-EP892330HU
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Source E.coli
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Code CSB-EP892330HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP892330HU
MSDS
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Source Baculovirus
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Code CSB-MP892330HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
PITPNC1
Uniprot No.
Alternative Names
Cytoplasmic phosphatidylinositol transfer protein 1; M rdgB beta; M-rdgB beta; Mammalian rdgB homolog beta; MrdgBbeta; Phosphatidylinositol transfer protein cytoplasmic 1; PITC1_HUMAN; pitpnc1; RDGB BETA; RDGBB; RDGBB1; RdgBbeta; Retinal degeneration B beta 1; Retinal degeneration B homolog beta
Species
Homo sapiens (Human)
Expression Region
1-332
Target Protein Sequence
MLLKEYRICM PLTVDEYKIG QLYMISKHSH EQSDRGEGVE VVQNEPFEDP HHGNGQFTEK RVYLNSKLPS WARAVVPKIF YVTEKAWNYY PYTITEYTCS FLPKFSIHIE TKYEDNKGSN DTIFDNEAKD VEREVCFIDI ACDEIPERYY KESEDPKHFK SEKTGRGQLR EGWRDSHQPI MCSYKLVTVK FEVWGLQTRV EQFVHKVVRD ILLIGHRQAF AWVDEWYDMT MDDVREFERA TQEATNKKIG IFPPAISISS IPLLPSSVRS APSSAPSTPL STDAPEFLSV PKDRPRKKSA PETLTLPDPE KKATLNLPGM HSSDKPCRPK SE
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidic acid (PA) between membranes. Binds PA derived from the phospholipase D signaling pathway and among the cellular PA species, preferably binds to the C16:0/16:1 and C16:1/18:1 PA species.; Catalyzes the transfer of phosphatidylinositol between membranes.
Gene References into Functions
  1. PITPNC1-mediated vesicular release. PMID: 26977884
  2. Phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) binds and transfers phosphatidic acid PMID: 22822086
  3. The most significantly associated SNPs to type 2 diabetes mellitus in this study are expression SNPs to the lymphocyte antigen 75 gene, the ubiquitin-specific peptidase 36 gene, and the phosphatidylinositol transfer protein, cytoplasmic 1 gene. PMID: 22865700
Subcellular Location
Cytoplasm.
Protein Families
PtdIns transfer protein family, PI transfer class IIB subfamily
Tissue Specificity
Ubiquitously expressed.
Database Links

HGNC: 21045

OMIM: 605134

KEGG: hsa:26207

STRING: 9606.ENSP00000335618

UniGene: Hs.591185

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