Recombinant Human Fc receptor-like B (FCRLB)

Code CSB-YP008561HU
MSDS
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Source Yeast
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Code CSB-EP008561HU
MSDS
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Source E.coli
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Code CSB-EP008561HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP008561HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP008561HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
FCRLB
Uniprot No.
Alternative Names
FCRLB; FCRL2; FCRLM2; FCRY; FREB2Fc receptor-like B; Fc receptor homolog expressed in B-cells protein 2; FREB-2; Fc receptor-like and mucin-like protein 2; Fc receptor-like protein 2; Fc receptor-related protein Y; FcRY
Species
Homo sapiens (Human)
Expression Region
18-426
Target Protein Sequence
ATL EKPILSLHPP WTTIFKGERV TLKCDGYHPL LLELQPISTL WYLGHLLLPS HKKSIEVQTP GVYRCQTRGA PVSDPIHLSV SNDWLILQVP YAPVFEGEPL VLRCRGWYDK VVYKLHYYHD GQAVRYFHSS ANYTVLQARA SDSGRYQCSG TMRIPVESAP MFSAKVAVTV QELFRAPVLR VMGPREARGA ALGGVVLRCD TRLHPQKRDT PLQFAFYKYS RAVRRFDWGA EYTVPEPEVE ELESYWCEAA TATRSVRKRS PWLQLPGPGS PLDPASTTAP APWAAALAPG NRPLSFRKPP VSRSVPLVTS VRNTTSTGLQ FPASGAPTAG PPACAPPTPL EQSAGALKPD VDLLLREMQL LKGLLSRVVL ELKEPQALRE LRGTPETPTS HFAVSPGTPE TTPVES
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Gene References into Functions
  1. The aim of the study was to associate multiple polymorphisms within FCGR gene locus with IgA nephropathy in a large Chinese cohort. PMID: 23593433
  2. Expression analysis revealed FCRL2 mRNA only in placenta.FCRL2 is differentially expressed by transformed B cell lines. PMID: 15676285
  3. Fcry is upregulated by short-term treatment with BAFF/BLyS, which promotes B cell survival rather than proliferation PMID: 16263223
Subcellular Location
Cytoplasm. Endoplasmic reticulum.
Tissue Specificity
Expressed at low levels. Expressed in B-lymphocytes. Detected in tonsil, lung, kidney, spleen and placenta. Expressed by a small subset of germinal center B-cells in tonsils and by melanocytes (at protein level).
Database Links

HGNC: 26431

OMIM: 609251

KEGG: hsa:127943

UniGene: Hs.517422

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