Recombinant Human Hippocalcin-like protein 1 (HPCAL1)

Code CSB-YP010695HU
MSDS
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Source Yeast
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Code CSB-EP010695HU
MSDS
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Source E.coli
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Code CSB-EP010695HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP010695HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP010695HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
HPCAL1
Uniprot No.
Alternative Names
BDR1; Calcium binding protein BDR1; Calcium-binding protein BDR-1; hippocalcin like 1; Hippocalcin-like protein 1; HLP2; HPCAL1; HPCAL1 protein; HPCL1_HUMAN; REM-1; VILIP-3; Visinin like protein 3; Visinin-like protein 3
Species
Homo sapiens (Human)
Expression Region
2-193
Target Protein Sequence
GKQNSKLRP EVLQDLRENT EFTDHELQEW YKGFLKDCPT GHLTVDEFKK IYANFFPYGD ASKFAEHVFR TFDTNGDGTI DFREFIIALS VTSRGKLEQK LKWAFSMYDL DGNGYISRSE MLEIVQAIYK MVSSVMKMPE DESTPEKRTD KIFRQMDTNN DGKLSLEEFI RGAKSDPSIV RLLQCDPSSA SQF
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.
Gene References into Functions
  1. The myristoylated VILIP-3 protein structure determined in this study is quite different. PMID: 27820860
  2. Secreted HPCAL1 protein in the plasma dropped dramatically in hepatocellular carcinoma patients relative to controls. PMID: 26659654
  3. Results show that in the presence of calcium, N-myristoylation significantly increases the kinetic rate of VILIP adsorption to the membrane. PMID: 25019684
  4. HPCAL1 did not appreciably influence the ability of WT PHOX2B. PMID: 23873030
  5. visinin-like protein-3 interacts with microsomal cytochrome b5 in a Ca2+-dependent manner PMID: 14739275
  6. The interaction of human VILIP1 and VILIP3 with divalent cations was explored using circular dichroism and fluorescence measurement. PMID: 16703469
  7. VILIP-3 immunostaining was found to be reduced in Alzheimer brains; immunoreactive material was detected in close association with amyloid plaques and neurofibrillar tangles, typical pathologic hallmarks of AD PMID: 11173883

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Subcellular Location
Membrane; Lipid-anchor.
Protein Families
Recoverin family
Database Links

HGNC: 5145

OMIM: 600207

KEGG: hsa:3241

STRING: 9606.ENSP00000310749

UniGene: Hs.580427

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