Recombinant Human Leucine-rich repeats and immunoglobulin-like domains protein 2 (LRIG2), partial

Code CSB-YP013085HU
MSDS
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Source Yeast
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Code CSB-EP013085HU
MSDS
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Source E.coli
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Code CSB-EP013085HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP013085HU
MSDS
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Source Baculovirus
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Code CSB-MP013085HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
LRIG2
Uniprot No.
Alternative Names
KIAA0806; Leucine rich repeats and immunoglobulin like domains 2; Leucine-rich repeats and immunoglobulin-like domains protein 2; LIG-2; LIG2; LRIG2; LRIG2_HUMAN; UFS2
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Gene References into Functions
  1. Study demonstrated that LRIG2 promoted the PDGFRBinduced proliferation of glioblastoma multiforme cells in vitro and in vivo through regulating the PDGFRB signalingmediated cell cycle progression. PMID: 30015847
  2. Role of LRIG2 in cancer [review] PMID: 27628597
  3. LRIG2 gene is overexpressed in invasive pituitary adenoma. PMID: 21823015
  4. A subset of urofacial syndrome-affected individuals have biallelic mutations in LRIG2 PMID: 23313374
  5. Cytoplasmic expression of LRIG2 is associated with meningiomas. PMID: 22484910
  6. LRIG1 and LRIG2 expressions were seen in precancerous cervical epithelium and found to increase with increasing grade. PMID: 21632100
  7. LRIG2 was found to be a glycoprotein with an molecular weight of 132 kDa, which was encoded by a gene on human chromosome 1p13 and its mRNA was present in all tissues analyzed. PMID: 15145052
  8. LRIG proteins may have a role in epidermal homeostasis and psoriasis PMID: 18037903
  9. This is the first report of an LRIG protein showing a negative effect on survival, suggesting that LRIG2 might have a function different from that of LRIG1, and possibly contributing to the etiology of oligodendroglioma. PMID: 18992012

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Involvement in disease
Urofacial syndrome 2 (UFS2)
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Tissue Specificity
Detected in all tissues analyzed.
Database Links

HGNC: 20889

OMIM: 608869

KEGG: hsa:9860

STRING: 9606.ENSP00000355396

UniGene: Hs.448972

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