LRIG2 Antibody

Code CSB-PA013085LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: HepG2 whole cell lysate
    All lanes: LRIG2 antibody at 3.5μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 119 kDa
    Observed band size: 119 kDa

  • Immunofluorescence staining of Hela cells with CSB-PA013085LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LRIG2 Polyclonal antibody
Uniprot No.
Target Names
LRIG2
Alternative Names
KIAA0806 antibody; Leucine rich repeats and immunoglobulin like domains 2 antibody; Leucine-rich repeats and immunoglobulin-like domains protein 2 antibody; LIG-2 antibody; LIG2 antibody; LRIG2 antibody; LRIG2_HUMAN antibody; UFS2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Leucine-rich repeats and immunoglobulin-like domains protein 2 protein (833-932AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The LRIG2 Antibody (Product code: CSB-PA013085LA01HU) is Non-conjugated. For LRIG2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA013085LB01HU LRIG2 Antibody, HRP conjugated ELISA
FITC CSB-PA013085LC01HU LRIG2 Antibody, FITC conjugated
Biotin CSB-PA013085LD01HU LRIG2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Study demonstrated that LRIG2 promoted the PDGFRBinduced proliferation of glioblastoma multiforme cells in vitro and in vivo through regulating the PDGFRB signalingmediated cell cycle progression. PMID: 30015847
  2. Role of LRIG2 in cancer [review] PMID: 27628597
  3. LRIG2 gene is overexpressed in invasive pituitary adenoma. PMID: 21823015
  4. A subset of urofacial syndrome-affected individuals have biallelic mutations in LRIG2 PMID: 23313374
  5. Cytoplasmic expression of LRIG2 is associated with meningiomas. PMID: 22484910
  6. LRIG1 and LRIG2 expressions were seen in precancerous cervical epithelium and found to increase with increasing grade. PMID: 21632100
  7. LRIG2 was found to be a glycoprotein with an molecular weight of 132 kDa, which was encoded by a gene on human chromosome 1p13 and its mRNA was present in all tissues analyzed. PMID: 15145052
  8. LRIG proteins may have a role in epidermal homeostasis and psoriasis PMID: 18037903
  9. This is the first report of an LRIG protein showing a negative effect on survival, suggesting that LRIG2 might have a function different from that of LRIG1, and possibly contributing to the etiology of oligodendroglioma. PMID: 18992012

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Involvement in disease
Urofacial syndrome 2 (UFS2)
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Tissue Specificity
Detected in all tissues analyzed.
Database Links

HGNC: 20889

OMIM: 608869

KEGG: hsa:9860

STRING: 9606.ENSP00000355396

UniGene: Hs.448972

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